N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
Hydroxy Desmethyl Bosentan
CAS: 253688-62-9
Molecular Formula: C26H27N5O7S
N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide - Names and Identifiers
| Name | Hydroxy Desmethyl Bosentan |
| Synonyms | Ro 64-1056 Hydroxy Desmethyl Bosentan HYDROXY DESMETHYL BOSENTAN Bosentan Hydroxy methyl O-Desmethyl-Imp O-Desmethyl Bosentan Hydroxymethyl Analog Bosentan HydroxyMethyl O-DesMethyl IMpurity 4-(2-Hydroxy-1,1-diMethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyriMidin]-4-yl]benzenesulfonaMide Benzenesulfonamide, 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2'-bipyrimidin]-4-yl]- N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide |
| CAS | 253688-62-9 |
N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide - Physico-chemical Properties
| Molecular Formula | C26H27N5O7S |
| Molar Mass | 553.58688 |
| Density | 1.426±0.06 g/cm3(Predicted) |
| Melting Point | >200°C (dec.) |
| Boling Point | 782.0±70.0 °C(Predicted) |
| Solubility | Methanol |
| Appearance | Solid |
| Color | Light Yellow to Yellow |
| pKa | 3.81±0.10(Predicted) |
| Storage Condition | -20°C Freezer |
N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide - Introduction
Hydroxy Desmethyl Bosentan is one of the metabolites of Bosentan. Its chemical structure contains hydroxyl and demethyl groups.
Regarding properties, as an organic compound, Hydroxy Desmethyl Bosentan has some physical and chemical properties. However, due to the lack of specific experimental data, it is difficult to give a detailed description.
Hydroxy Desmethyl Bosentan is mainly used to study the Pharmacokinetics (Pharmacokinetics) and metabolic process of Bosentan. As a metabolite of Bosentan, the metabolic mechanism of Bosentan in vivo can be better understood by studying the generation, transformation and clearance rates of hydrodesmethyl Bosentan.
regarding the preparation method, Hydroxy Desmethyl Bosentan is usually obtained through in vitro metabolism experiments. That is, Bosentan reacts with the corresponding metabolic enzymes or tissues together, and then hydrodesmethyl Bosentan is isolated and purified.
Regarding safety information, since Hydroxy Desmethyl Bosentan is a metabolite used for research purposes, there is no detailed safety data for reference. However, when conducting experiments, laboratory safety regulations should be observed and appropriate protective measures should be taken to avoid contact and exposure to its high concentrations.
Regarding properties, as an organic compound, Hydroxy Desmethyl Bosentan has some physical and chemical properties. However, due to the lack of specific experimental data, it is difficult to give a detailed description.
Hydroxy Desmethyl Bosentan is mainly used to study the Pharmacokinetics (Pharmacokinetics) and metabolic process of Bosentan. As a metabolite of Bosentan, the metabolic mechanism of Bosentan in vivo can be better understood by studying the generation, transformation and clearance rates of hydrodesmethyl Bosentan.
regarding the preparation method, Hydroxy Desmethyl Bosentan is usually obtained through in vitro metabolism experiments. That is, Bosentan reacts with the corresponding metabolic enzymes or tissues together, and then hydrodesmethyl Bosentan is isolated and purified.
Regarding safety information, since Hydroxy Desmethyl Bosentan is a metabolite used for research purposes, there is no detailed safety data for reference. However, when conducting experiments, laboratory safety regulations should be observed and appropriate protective measures should be taken to avoid contact and exposure to its high concentrations.
Last Update：2024-04-09 21:54:55
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Product Name: Bosentan Impurity 3 Visit Supplier Webpage Request for quotationCAS: 253688-62-9
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Mobile: 86+15671228036
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CAS: 253688-62-9
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CAS: 253688-62-9
Tel: 18301782025
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Mobile: 18021002903
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